| Academic lectures:Decoding Collagen - Computational Modeling and Design of Fibrous Proteins |
| Published date：2014-07-16 Provided by：School of Science |
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Title: Decoding Collagen - Computational Modeling and Design of Fibrous Proteins
Guest Speaker：Dr.Xu Fei, the State University of New Jersey
Time：2014-7-11, 15:00 – 16:00 Location：Meeting Room2210, School of Science
Content &Introduction：
As the most abundant protein in human, collagen serves as a scaffold of biological processes in extracellular connective matrix. Collagen has also been widely utilized as bioactive cell culture substrates in tissue engineering. Here, I approach biophysical and biomechanical properties of collagen in three aspects (1) computational design of specific heterotrimers; (2) morphological and rheological study of collagen higher-order assembly; (3) statistical mechanical modeling of collagen triple helix deformability. Insight gained from this study will lead to the improved molecular design of biomimetic smart materials. |