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 Personal Information |
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- Title：Member of the CAE, Professor, M.D., Ph.D.
- Position：Head of Acadamician’s Lab in the Institute for Viral Disease Control and Prevention, China CDC; honorary director of College of Life Sciences and Bioengineering, Beijing Jiaotong University
- Tel：010-51683887 (O)
- E-mail：hongt@cae.cn
- Present Address：School of Science, Beijing Jiaotong University, No 3. Shangyuancun, Haidian District, Beijing, P.R.China, 100044
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| Education |
- 1955-1960, Institute of Virology, Romania Academy of Sciences, Bucharest, Ph.D., Medical Virology
- 1949-1955, Shandong Medical College, Ji’nan, Shandong, M.D., Medicine
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| Research Interest |
| Molecular virology: Viral structure, morphogenesis and EM Diagnosis; Mechanism of virus-host cell interaction Prion, Alzheimer’s disease and neurodegenerative disease: Cell and molecular mechanism of infectious and non-infectious dementia; Transmission and pathway of amyloid protein from cell to cell; Diagnostic and therapeutic strategy |
| Funding |
- National Major Scientific and Technological Special Project for "AIDS and Viral Hepatitis and Other Major Infectious Diseases Prevention and Control" (2013ZX10004-601), “High throughput screening platform for the biomarkers of pathogens for diagnosis and treatment by chemical genomics”. 2013-2015.
- Key Technologies Research and Development Program of China “Detection methods for pathogenic microorganism in diagnosis of major infectious diseases”. 2008-2010.
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| Major Publication |
- Yuan-Hui Fu, Yue-Ying Jiao, Jinsheng He, Gui-Yun Jiang, Wei Zahng, Yao Ma, Ying Zhang, Chang-Xin Shi, Xiang-Lei Peng, Tao Hong, Yi-Fei Yan. Sublingual administration of a helper-dependent adenoviral vector expressing the codon-optimized soluble fusion glycoprotein of human respiratory syncytial virus elicits protective immunity in mice. Antiviral Research. 2014, in press, AVR3386
- Zhang Y, Hung T, Song J, He J. Electron microscopy: essentials for viral structure, morphogenesis and rapid diagnosis. Sci China Life Sci, 2013, 56 (5) : 421-430
- Guo L, Wang Y, Zhou H, Wu C, Song J, Li J, Paranhos-Baccalà G, Vernet G, Wang J, Hung T. Differential seroprevalence of human bocavirus species 1-4 in Beijing, China. PLoS One, 2012, 7(6): e39644
- Liu Y, Wei H, Qu J, Wang J, Hung T. Prefibrillar aggregates of yeast prion Sup35NM and its variant are toxic to mammalian cells. Neurol Sci, 2011, 32 (6):1147-1152
- Zhang Y, He JS, Wang X, Wang J, Bao FX, Pang SY, Yin F, Hu HG, Peng XL, Sun WM, Zheng YP, Hou LL, Hong T. Administration of Ab1-42 Oligomers Specific Monoclonal Antibody Improved Memory Performance in SAMP8 Mice. J Alzheimers Dis, 2011, 23 (3): 551-561
- Zhao L, Hou X, Ji R, Han C, Yu X, Hong T. Establishment of bovine prion peptide-based monoclonal antibodies for identifying bovine prion. Sci China C Life Sci, 2009, 52(8) : 754-760
- Liu Y, Wei H, Wang J, Qu J, Zhao W, Hung T. Effects of randomizing the Sup35NM prion domain sequence on formation of amyloid ?brils in vitro. Biochem Biophys Res Commun, 2007, 353 (1):139-146
- Zhang Y, Qin K, Wang J, Hung T, Zhao RY. Dividing roles of prion protein in staurosporine-mediated apoptosis. Biochem Biophys Res Commun, 2006, 349 (2) : 759-768
- Chen C(G)M, Hung T, Bridger JC, McCrae MA. Chinese adult rotavirus is a group B rotavirus. Lancet, 1985, 2 (8464):1123-1124
- Hung T, Fan RL, Wang CA, Chen GM, Chou DN, Chang JQ, McCrae MA, Wang WZ, Se WZ, Dan R, et al. Seroepidemiology of adult rotavirus. Lancet, 1985, 2 (8450): 325-326
- Hung T, Chen GM, Wang CG, Yao HL, Fang ZY, Chao TX, Chou ZY, Ye W, Chang XJ, Den SS, et al. Waterborne outbreak of rotavirus diarrhoea in adults in China caused by a novel rotavirus. Lancet, 1984, 1(8387): 1139-1142
- Hung T, Chen GM, Wang CG, Chou ZY, Chao TX, Ye WW, Yao HL, Meng KH. Rotavirus-like agent in adult non-bacterial diarrhoea in China. Lancet, 1983, 2 (8358):1078-1079
- Hung T, Xia SM, Song G, Liao HX, Chao TX, Chou ZY, Hang CS. Viruses of Classical and Mild Forms of Haemorrhagic Fiver with Renal Syndrome Isolated in China Have Similar Bunyavirus-like Morphology. Lancet, 1983, 1(8324):589-591
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| Awards＆Honors |
- He-Liang-He-Li Prize for Science and Technology Achievements, 1997
- National Award for Science and Technology Advancement (Class II) for molecular studies on ADRV, 1996
- Award for Science and Technology Advancement (Class II) for studies on ADRV, 1994
- Honorary Award, Meritous Service Award, WHO Collaborating Center for Virus Reference and Research& Inst. Virology, Korea, Seoul, 1993
- First Class Award for The Atlas of HFRS, 5th National Committee for Outstanding Books in the field of Science & Technology, 1990
- WHO 1986 grant awarded for Adult Diarrhea Rotavirus (ADRV)
- WHO 1988 grant awarded for the Development of Rapid Diagnosis of ADRV
- National Nature Science Award (III), China National Commission for Nature Sciences for outstanding contribution in studying HFRS, 1989
- National Nature Science Award (III) for the outstanding contribution in study of Adult Diarrhea Rotavirus (ADRV),awarded by China National
- Commission for Nature Science, Achievement Awarding
- Commemorative awards (Certificates of Merit) of International WHO'S
- WHO IN MEDICINE--FIRST EDITION, Cambridge, England, 1986
- Specialist with outstanding contribution, awarded by the National Commission for Science and Technology, China, 1986
- First Class Award for the Discovery of Adult Diarrhoea Rotavirus (ADRV), 1985 Ministry of Health
- Achievement Awards for Contributions on the New Developments of Biomedical Electron Microscopy, 1979, 1980 and 1983.
- First Class Achievement Award for the Discovery of Morphology and Morphogenesis of HFRS Viruses, 1984, Ministry of Health.
- Awarded at the National Congress of Medical Sciences for the Contributions on Ultrastructural Research of an Ancient Cadaver of 2200 years (Han Dynasty), 1978
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